Article
Acteoside Repressed Microglia M1 Polarization Through Inhibited NF-κB Signalling Pathway and AMPK-Mediated Mitochondria Function Recovery
2020-12-16
Abstract excerpt
<title>Abstract</title> <p><bold>Background</bold>: Alzheimer's disease (AD) is the most frequent type of dementia. While acteoside (ACT), a compound isolated from <italic>Cistanche tubulosa</italic>, possesses neuroprotective properties. However, the underlying mechanism in regulating microglia polarization remains ill-defined. <bold>Methods:</bold> Herein, AlCl<sub>3</sub>-induced AD model in zebrafish larvae w...
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Identifiers and source
- Literature Corpus work
- ba272645-bb7e-5f98-ae2d-a8ad627cc0cf
- DOI
- 10.21203/rs.3.rs-127246/v1
