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The Synergistic Effect Study of Lipopolysaccharide (LPS) and A53T-α-synuclein: Intranasal LPS Exposure on the A53T-α-synuclein Transgenic Mouse Model of Parkinson's Disease

2023-09-05

Abstract excerpt

<title>Abstract</title> <p>Aging and the interaction between genetic and environmental factors are believed to be involved in chronic Parkinson's Disease (PD) progression. Abnormal aggregated α-synuclein is the main component of Lewy body in PD patients. The intranasal route is believed to be a gate way to the brain which facilitates entry of environmental neurotoxin into the brain and account for the smell loss...

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Literature Corpus work
8b269284-6e75-56c3-af20-ef3ff9308b4e
DOI
10.21203/rs.3.rs-3312011/v1
Open publication

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