Article

Repeated low-intensity focused ultrasound induces microglial profile changes in the TgF344-AD rat model of Alzheimer’s disease

2024-09-27

Abstract excerpt

Alzheimer’s disease (AD), the most common cause of dementia, represents one of the main clinical challenges of the century as the number of patients is predicted to triple by 2050. Despite the recent approval of three monoclonal antibodies targeting Amyloid β (Aβ) aggregates by the Food and Drug Administration (FDA), immunotherapies still face challenges due to the difficulty of antibodies crossing the blood-brain...

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Literature Corpus work: ae039288-adf6-5aba-b24c-14d93dea94f1
DOI: 10.1101/2024.09.25.614692

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