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Investigating the Therapeutic Potential of Uric Acid in Alzheimer's Disease: Insights from the cGMP-PKG Signaling Pathway

2024-03-05

Abstract excerpt

<h4>Background: </h4> Alzheimer's disease (AD) is characterized by neuroinflammation and oxidative stress, both contributing to disease progression. Uric acid (UA) has emerged as a potential therapeutic agent due to its anti-inflammatory and antioxidative properties. However, the precise mechanisms underlying UA's role in AD pathogenesis remain unclear. <h4>Methods: </h4>: BV2 microglial cells were subjected to t...

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Literature Corpus work: caf1fc64-da15-5e47-a1c2-ec8946606c7b
DOI: 10.21203/rs.3.rs-3999543/v1

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