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Article

Sex Differences in Alzheimer's Disease: Insights From the Multiomics Landscape.

Biological psychiatry - 1 Jan 2022

Guo Lei, Zhong Margaret B, Zhang Larry, Zhang Bin, Cai Dongming

Abstract excerpt

Alzheimer's disease (AD) has complex etiologies, and the impact of sex on AD varies over the course of disease development. The literature provides some evidence of sex-specific contributions to AD. However, molecular mechanisms of sex-biased differences in AD remain elusive. Multiomics data in tandem with systems biology approaches offer a new avenue to dissect sex-stratified molecular mechanisms of AD and to...

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Identifiers

PMID: 33896621
DOI: 10.1016/j.biopsych.2021.02.968
PMCID: PMC8996342

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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