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Article

Genome-wide analysis of genetic predisposition to Alzheimer’s disease and related sex-disparities

2018-05-15

Abstract excerpt

<h4>Background</h4> Alzheimer’s disease (AD) is the most common cause of dementia in the elderly and the sixth leading cause of death in the United States. AD is mainly considered a complex disorder with polygenic inheritance. Despite discovering many susceptibility loci, a major proportion of AD genetic variance remains to be explained. <h4>Methods</h4> We investigated the genetic architecture of AD in four pub...

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Literature Corpus work
899e8601-663b-501c-98e1-3e4dc6b9c294
DOI
10.1101/321992
Open publication

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Genome-wide analysis of genetic predisposition to Alzheimer’s disease and related sex-disparitiesDOI 10.1101/321992
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