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Article

Sex specific molecular networks and key drivers of Alzheimer’s disease

20 Jun 2023

Abstract excerpt

BACKGROUND: Alzheimer's disease (AD) is a progressive and age-associated neurodegenerative disorder that affects women disproportionally. However, the underlying mechanisms are poorly characterized. Moreover, while the interplay between sex and ApoE genotype in AD has been investigated, multi-omics studies to understand this interaction are limited. Therefore, we applied systems biology approaches to investigate...

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PMID: 37340466
DOI: 10.1186/s13024-023-00624-5

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