Article
Genome-wide association study of serum metabolites in the African American Study of Kidney Disease and Hypertension.
Kidney international - 1 Aug 2021
Luo Shengyuan, Feofanova Elena V, Tin Adrienne, Tung Sarah, Rhee Eugene P, Coresh Josef, Arking Dan E, Surapaneni Aditya, Schlosser Pascal, Li Yong, Köttgen Anna, Yu Bing, Grams Morgan E
Abstract excerpt
The genome-wide association study (GWAS) is a powerful means to study genetic determinants of disease traits and generate insights into disease pathophysiology. To date, few GWAS of circulating metabolite levels have been performed in African Americans with chronic kidney disease. Hypothesizing that novel genetic-metabolite associations may be identified in a unique population of African Americans with a lower...
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