Article
MetaboXcan: A multiomic framework linking genetically predicted metabolites, gene expression, and complex traits
2026-07-17
Abstract excerpt
Genetically regulated molecular phenotypes, such as gene expression and metabolites, are widely thought to mediate the effect of disease-relevant genetic loci identified by genome-wide association studies (GWAS); however, molecular mechanisms connecting genetic variation to disease remain poorly understood. While transcriptome-wide association studies (TWAS) have identified disease-associated genes, strategies tha...
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Identifiers and source
- Literature Corpus work
- 5d750388-9b7b-5b6e-a7a6-447f3bc28ab5
- DOI
- 10.64898/2026.07.15.738631