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Article

Do Current Measures of Polygenic Risk for Mental Disorders Contribute to Population Variance in Mental Health?

Schizophrenia bulletin - 1 Dec 2020

Marsman Anne, Pries Lotta-Katrin, Ten Have Margreet, de Graaf Ron, van Dorsselaer Saskia, Bak Maarten, Kenis Gunter, Lin Bochao D, Luykx Jurjen J, Rutten Bart P F, Guloksuz Sinan, van Os Jim

Abstract excerpt

The polygenic risk score (PRS) allows for quantification of the relative contributions of genes and environment in population-based studies of mental health. We analyzed the impact of transdiagnostic schizophrenia PRS and measures of familial and environmental risk on the level of and change in general mental health (Short-Form-36 mental health) in the Netherlands Mental Health Survey and Incidence Study-2...

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Identifiers

PMID: 33259628
DOI: 10.1093/schbul/sbaa086
PMCID: PMC7707067

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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