Article

Polygenic Scores and Environmental Factors in Psychiatric Disorders: Gene–Environment Interaction Analyses Using the iPSYCH Study

2025-10-08

Abstract excerpt

<h4>Background</h4> Psychiatric disorders represent a significant global health burden with complex etiologies involving both genetic and environmental factors. However, while the main effects of genetic and environmental factors are frequently studied, their interplay in shaping psychiatric disorder risk remains poorly understood. This study investigates the interaction between polygenic scores (PGS) as proxies...

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Literature Corpus work: a492e0ea-2bbf-59eb-9f85-0927fda42fde
DOI: 10.1101/2025.10.07.25337407

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