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Article

Specificity of polygenic scores for psychiatric disorders beyond transdiagnostic genetic risk (p)

2025-06-13

Abstract excerpt

<h4>Importance</h4> Polygenic scores are increasingly used to estimate genetic liability for psychiatric disorders. However, their limited specificity to the disorders for which they are derived limits their clinical and research utility. <h4>Objective</h4> To determine whether associations between polygenic scores for major psychiatric disorders and psychopathology outcomes are primarily driven by transdiagnostic...

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Literature Corpus work
25decfdb-6b70-58ab-ab4d-a40f6284167e
DOI
10.1101/2025.06.12.25329497
Open publication

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Specificity of polygenic scores for psychiatric disorders beyond transdiagnostic genetic risk (p)DOI 10.1101/2025.06.12.25329497
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