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Article

Phospho-Mimetic Mutation at Ser602 Inactivates Human TRPA1 Channel.

International journal of molecular sciences - 27 Oct 2020

Barvikova Kristyna, Barvik Ivan, Sinica Viktor, Zimova Lucie, Vlachova Viktorie

Abstract excerpt

The Transient Receptor Potential Ankyrin 1 (TRPA1) channel is an integrative molecular sensor for detecting environmental irritant compounds, endogenous proalgesic and inflammatory agents, pressure, and temperature. Different post-translational modifications participate in the discrimination of the essential functions of TRPA1 in its physiological environment, but the underlying structural bases are poorly...

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Identifiers

PMID: 33121177
DOI: 10.3390/ijms21217995
PMCID: PMC7663402

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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