Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functionally important amino acid residues in the transient receptor potential vanilloid 1 (TRPV1) ion channel--an overview of the current mutational data.

Molecular pain - 22 Jun 2013

Winter Zoltán, Buhala Andrea, Ötvös Ferenc, Jósvay Katalin, Vizler Csaba, Dombi György, Szakonyi Gerda, Oláh Zoltán

Abstract excerpt

This review aims to create an overview of the currently available results of site-directed mutagenesis studies on transient receptor potential vanilloid type 1 (TRPV1) receptor. Systematization of the vast number of data on the functionally important amino acid mutations of TRPV1 may provide a clearer picture of this field, and may promote a better understanding of the relationship between the structure and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Binding Sites

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to TRPV1 gene

Share to Models, Biological

Share to Mutagenesis, Site-Directed

Share to Mutation

Share to TRPV Cation Channels

Source

Open in PubMed Open full text

Identifiers

PMID: 23800232
DOI: 10.1186/1744-8069-9-30
PMCID: PMC3707783

Genes

TRPV1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functionally important amino acid residues in the transient receptor potential vanilloid 1 (TRPV1) ion channel--an overview of the current mutational data.PMID 23800232Read ↗

Identification of molecular determinants of channel gating in the transient receptor potential box of vanilloid receptor I.Semantic proximity Read ↗

Missense variant analysis in the TRPV1 ARD reveals the unexpected functional significance of a methionineSemantic proximity Read ↗

TRPV1.Semantic proximity Read ↗

Gain-of-function mutations in the transient receptor potential channels TRPV1 and TRPA1: how painful?Semantic proximity Read ↗

Agonist-dependence of functional properties for common nonsynonymous variants of human transient receptor potential vanilloid 1.Semantic proximity Read ↗

TRPing to the Point of Clarity: Understanding the Function of the Complex TRPV4 Ion Channel.Semantic proximity Read ↗

The TRPV4 channel.Semantic proximity Read ↗

Temperature-induced opening of TRPV1 ion channel is stabilized by the pore domain.Semantic proximity Read ↗

Contribution of the putative inner-pore region to the gating of the transient receptor potential vanilloid subtype 1 channel (TRPV1).Semantic proximity Read ↗

TRPV1 temperature activation is specifically sensitive to strong decreases in amino acid hydrophobicity.Semantic proximity Read ↗

Polymodal Transient Receptor Potential Vanilloid Type 1 Nocisensor: Structure, Modulators, and Therapeutic Applications.Semantic proximity Read ↗

A tyrosine residue in TM6 of the Vanilloid Receptor TRPV1 involved in desensitization and calcium permeability of capsaicin-activated currents.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.