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Article

Diploid genome architecture revealed by multi-omic data of hybrid mice.

Genome research - 1 Aug 2020

Han Zhijun, Cui Kairong, Placek Katarzyna, Hong Ni, Lin Chengqi, Chen Wei, Zhao Keji, Jin Wenfei

Abstract excerpt

Although mammalian genomes are diploid, previous studies extensively investigated the average chromatin architectures without considering the differences between homologous chromosomes. We generated Hi-C, ChIP-seq, and RNA-seq data sets from CD4 T cells of B6, Cast, and hybrid mice, to investigate the diploid chromatin organization and epigenetic regulation. Our data indicate that inter-chromosomal interaction...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32759226
DOI: 10.1101/gr.257568.119
PMCID: PMC7462080

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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