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Article

Allele-specific control of replication timing and genome organization during development.

Genome research - 1 Jun 2018

Rivera-Mulia Juan Carlos, Dimond Andrew, Vera Daniel, Trevilla-Garcia Claudia, Sasaki Takayo, Zimmerman Jared, Dupont Catherine, Gribnau Joost, Fraser Peter, Gilbert David M

Abstract excerpt

DNA replication occurs in a defined temporal order known as the replication-timing (RT) program. RT is regulated during development in discrete chromosomal units, coordinated with transcriptional activity and 3D genome organization. Here, we derived distinct cell types from F1 hybrid musculus × castaneus mouse crosses and exploited the high single-nucleotide polymorphism (SNP) density to characterize allelic...

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Identifiers

PMID: 29735606
DOI: 10.1101/gr.232561.117
PMCID: PMC5991511

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CAST

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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