Article

Comparison of the 3D organization of sperm and fibroblast genomes using the Hi-C approach

2014-06-16

Abstract excerpt

The 3D organization of the genome is tightly connected to its biological function. The Hi-C approach was recently introduced as a method that can be used to identify higher-order chromatin interactions genome-wide. The aim of this study was to determine genome-wide chromatin interaction frequencies using the Hi-C approach in mouse sperm cells and embryonic fibroblasts. The obtained results demonstrated that the 3D...

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Literature Corpus work: 662805b6-2f42-5c3b-90c9-5f7ddd5965ad
DOI: 10.1101/006247

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