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Article

Bioinformatic Analysis of Single-Cell Hi-C Data from Early Mouse Embryo.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021

Collombet Samuel, Pérez-Rico Yuvia A, Ancelin Katia, Servant Nicolas, Heard Edith

Abstract excerpt

The adaptation of Hi-C protocols to enable the investigation of chromosome organization in single cells opens new avenues to study the dynamics of this process during embryogenesis. However, the analysis of single-cell Hi-C data is not yet standardized and raises novel bioinformatic challenges. Here we describe a complete workflow for the analysis of single-cell Hi-C data, with a main focus on allele-specific...

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PMID: 32944918
DOI: 10.1007/978-1-0716-0958-3_20

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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