Article

Dynamics of genome architecture and chromatin function during human B cell differentiation and neoplastic transformation

2019-09-10

Abstract excerpt

Despite recent advances, the dynamics of genome architecture and chromatin function during human cell differentiation and its potential reorganization upon neoplastic transformation remains poorly characterized. Here, we integrate in situ Hi-C and nine additional omic layers to define and biologically characterize the dynamic changes in three-dimensional (3D) genome architecture across normal B cell differentiati...

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Literature Corpus work: 59d0424d-7862-5856-8c19-79c08c1efd2a
DOI: 10.1101/764910

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