Article

Mitotic chromosomes harbor cell type and species-specific structural features within a universal looping architecture

2023-12-09

Abstract excerpt

The architecture of mammalian mitotic chromosomes is considered to be universal across species and cell types. However, some studies suggest that features of mitotic chromosomes might be cell type or species specific. We previously reported that CTCF binding in human differentiated cell lines is lost in mitosis, whereas mouse embryonic stem cells (mESC) display prominent binding at a subset of CTCF sites in mitosi...

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Literature Corpus work: cb10ee50-08d4-50f4-a870-21239ff06af7
DOI: 10.1101/2023.12.08.570796

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