Article

Three-dimensional Genome Structure Reveals Distinct Chromatin Signatures of Mouse Female Germline Stem Cells During Development

2019-09-30

Abstract excerpt

<h4>SUMMARY</h4> The three-dimensional configuration of the genome ensures cell-type-specific gene expression profiles by placing genes and regulatory elements in close spatial proximity. Here, we revealed the distinct features of the chromatin architecture in female germline stem cells (FGSCs) by in situ high-throughput chromosome conformation analysis. We also showed that the X chromosome structures were simil...

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Literature Corpus work: 11171925-26a6-5248-b931-f004f0415b3e
DOI: 10.1101/787689

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