Article

Highly structured homolog pairing reflects functional organization of the <i>Drosophila</i> genome

2018-10-17

Abstract excerpt

Trans -homolog interactions encompass potent regulatory functions, which have been studied extensively in Drosophila, where homologs are paired in somatic cells and pairing-dependent gene regulation, or transvection, is well-documented. Nevertheless, the structure of pairing and whether its functional impact is genome-wide have eluded analysis. Accordingly, we generated a diploid cell line from divergent parents...

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Literature Corpus work: e8306c34-91f6-5d21-924c-0fe91ccf8cd5
DOI: 10.1101/443887

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