Article
Neural network correlates of high-altitude adaptive genetic variants in Tibetans: A pilot, exploratory study.
Human brain mapping - 15 Jun 2020
Guo Zhiyue, Fan Cunxiu, Li Ting, Gesang Luobu, Yin Wu, Wang Ningkai, Weng Xuchu, Gong Qiyong, Zhang Jiaxing, Wang Jinhui
Abstract excerpt
Although substantial progress has been made in the identification of genetic substrates underlying physiology, neuropsychology, and brain organization, the genotype-phenotype associations remain largely unknown in the context of high-altitude (HA) adaptation. Here, we related HA adaptive genetic variants in three gene loci (EGLN1, EPAS1, and PPARA) to interindividual variance in a set of physiological...
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