Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Genome-Wide Search for Signals of High-Altitude Adaptation in Tibetans

20 Oct 2010

Abstract excerpt

Genetic studies of Tibetans, an ethnic group with a long-lasting presence on the Tibetan Plateau which is known as the highest plateau in the world, may offer a unique opportunity to understand the biological adaptations of human beings to high-altitude environments. We conducted a genome-wide study of 1,000,000 genetic variants in 46 Tibetans (TBN) and 92 Han Chinese (HAN) for identifying the signals of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue and Metabolism
Share to High Altitude and Hypoxia
Share to Metabolomics and Mass Spectrometry Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20961960
DOI: 10.1093/molbev/msq277

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Genome-Wide Search for Signals of High-Altitude Adaptation in TibetansPMID 20961960Read ↗

Genetic variations in Tibetan populations and high-altitude adaptation at the Himalayas.Semantic proximity Read ↗

Shared and unique signals of high-altitude adaptation in geographically distinct Tibetan populations.Semantic proximity Read ↗

Human adaptation to the hypoxia of high altitude: the Tibetan paradigm from the pregenomic to the postgenomic era.Semantic proximity Read ↗

Identifying signatures of natural selection in Tibetan and Andean populations using dense genome scan data.Semantic proximity Read ↗

Identification of a Tibetan-specific mutation in the hypoxic gene EGLN1 and its contribution to high-altitude adaptation.Semantic proximity Read ↗

Genetic evidence for high-altitude adaptation in Tibet.Semantic proximity Read ↗

Adaptive genetic changes related to haemoglobin concentration in native high-altitude Tibetans.Semantic proximity Read ↗

Genetic determinants of Tibetan high-altitude adaptation.Semantic proximity Read ↗

Sequencing of 50 human exomes reveals adaptation to high altitude.Semantic proximity Read ↗

Genome-wide analysis reveals adaptation to high altitudes in Tibetan sheep.Semantic proximity Read ↗

Differentiation analysis for estimating individual ancestry from the Tibetan Plateau by an archaic altitude adaptation EPAS1 haplotype among East Asian populations.Semantic proximity Read ↗

Transcriptomic analysis of iPSC-derived endothelium reveals adaptations to high altitude hypoxia in energy metabolism and inflammationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.