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Article

Adaptive genetic changes related to haemoglobin concentration in native high-altitude Tibetans.

Experimental physiology - 1 Nov 2015

Simonson T S, Huff C D, Witherspoon D J, Prchal J T, Jorde L B

Abstract excerpt

NEW FINDINGS: What is the topic of this review? Tibetans have genetic adaptations that are hypothesized to underlie the distinct set of traits they exhibit at altitude. What advances does it highlight? Several adaptive signatures in the same genomic regions have been identified among Tibetan populations resident throughout the Qinghai-Tibetan Plateau. Many highland Tibetans exhibit a haemoglobin concentration...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26454145
DOI: 10.1113/EP085035

Genes

EGLN1
EPAS1
PPARA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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