Article
Genetic evidence for high-altitude adaptation in Tibet.
Science (New York, N.Y.) - 2 Jul 2010
Simonson Tatum S, Yang Yingzhong, Huff Chad D, Yun Haixia, Qin Ga, Witherspoon David J, Bai Zhenzhong, Lorenzo Felipe R, Xing Jinchuan, Jorde Lynn B, Prchal Josef T, Ge RiLi
Abstract excerpt
Tibetans have lived at very high altitudes for thousands of years, and they have a distinctive suite of physiological traits that enable them to tolerate environmental hypoxia. These phenotypes are clearly the result of adaptation to this environment, but their genetic basis remains unknown. We report genome-wide scans that reveal positive selection in several regions that contain genes whose products are likely...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.