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Article

Hypobaric hypoxia drives selection of altitude-associated adaptative alleles in the Himalayan population.

The Science of the total environment - 25 Feb 2024

Sharma Samantha, Koshy Remya, Kumar Rahul, Mohammad Ghulam, Thinlas Tashi, Graham Brian B, Pasha Qadar

Abstract excerpt

Genetic variants play a crucial role in shaping the adaptive phenotypes associated with high-altitude populations. Nevertheless, a comprehensive understanding of the specific impacts of different environments associated with increasing altitudes on the natural selection of these genetic variants remains undetermined. Hence, this study aimed to identify genetic markers responsible for high-altitude adaptation with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38159773
DOI: 10.1016/j.scitotenv.2023.169605
PMCID: PMC11285711

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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