Population History and Altitude-Related Adaptation in the Sherpa

Abstract excerpt

The first ascent of Mount Everest by Tenzing Norgay and Sir Edmund Hillary in 1953 brought global attention to the Sherpa people and human performance at altitude. The Sherpa inhabit the Khumbu Valley of Nepal, and are descendants of a population that has resided continuously on the Tibetan plateau for the past ~25,000 to 40,000 years. The long exposure of the Sherpa to an inhospitable environment has driven...

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