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Article

Restricted and non-essential redundancy of RNAi and piRNA pathways in mouse oocytes.

PLoS genetics - 1 Dec 2019

Taborska Eliska, Pasulka Josef, Malik Radek, Horvat Filip, Jenickova Irena, Jelić Matošević Zoe, Svoboda Petr

Abstract excerpt

Germline genome defense evolves to recognize and suppress retrotransposons. One of defensive mechanisms is the PIWI-associated RNA (piRNA) pathway, which employs small RNAs for sequence-specific repression. The loss of the piRNA pathway in mice causes male sterility while females remain fertile. Unlike spermatogenic cells, mouse oocytes posses also RNA interference (RNAi), another small RNA pathway capable of...

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Identifiers

PMID: 31860668
DOI: 10.1371/journal.pgen.1008261
PMCID: PMC6944382

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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