Article

Golden hamster piRNAs are necessary for early embryonic development and establishment of spermatogonia

2021-01-28

Abstract excerpt

<h4>ABSTRACT</h4> PIWI-associated RNAs (piRNAs) support the germline by suppressing retrotransposons and genes. In mice, piRNAs are essential for spermatogenesis but not oogenesis. To test how this applies to other mammals, we deleted Mov10l1 helicase in golden hamster, whose piRNA pathway is configured more similarly to that of other mammals. Mov10l1 −/− male hamsters showed impaired establishment of spermato...

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Literature Corpus work: fb549f15-a980-58a6-aa33-3fbd08d63e86
DOI: 10.1101/2021.01.27.428513

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