Article
Restricted and non-essential redundancy of RNAi and piRNA pathways in mouse oocytes
2019-06-20
Abstract excerpt
Germline genome defense evolves to recognize and suppress retrotransposons. One of defensive mechanisms is the PIWI-associated RNA (piRNA) pathway, which employs small RNAs for sequence-specific post-transcriptional and transcriptional repression. The loss of the piRNA pathway in mice causes male sterility while females remain fertile. Unlike spermatogenic cells, mouse oocytes have also RNA interference (RNAi), an...
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Identifiers and source
- Literature Corpus work
- 177bdadf-4a14-52ce-8a03-c9d78d0d9efe
- DOI
- 10.1101/678177