Article

piRNA pathway is essential for generating functional oocytes in golden hamster

2021-03-22

Abstract excerpt

Piwi-interacting RNAs (piRNAs) are small RNAs predominantly expressed in germ cells that are critical for gametogenesis in various species. However, PIWI-deficient female mice are fertile and mouse oocytes express a panel of small RNAs that do not appear widely representative of mammals, and piRNA function in the oogenesis of other mammals has therefore remained elusive. Recent studies revealed the small RNA and...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5ef68253-4ad5-52e4-947b-91999cb2f2a1
DOI: 10.1101/2021.03.21.434510

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

piRNA pathway is essential for generating functional oocytes in golden hamsterDOI 10.1101/2021.03.21.434510Read

Production of functional oocytes requires maternally expressed <i>PIWI</i> genes and piRNAs in golden hamstersSemantic proximity Read

Golden hamster piRNAs are necessary for early embryonic development and establishment of spermatogoniaSemantic proximity Read

PIWIL3-piRNA Pathway Is Essential for Rabbit Oogenesis and Embryogenesis via Broad Regulation of the Transcriptome and ProteomeSemantic proximity Read

Integrated small and long RNA sequencing in single oocytes reveals piRNA-mediated transposon repression during human oogenesisSemantic proximity Read

Restricted and non-essential redundancy of RNAi and piRNA pathways in mouse oocytesSemantic proximity Read

Biology of PIWI-interacting RNAs: new insights into biogenesis and function inside and outside of germlines.Semantic proximity Read

piRNAs and their involvement in male germline development in mice.Semantic proximity Read

Restricted and non-essential redundancy of RNAi and piRNA pathways in mouse oocytes.Semantic proximity Read

Conserved small nucleotidic elements at the origin of concerted piRNA biogenesis from genes and lncRNAsSemantic proximity Read

RNF17 blocks promiscuous activity of PIWI proteins in mouse testes.Semantic proximity Read

Small RNAs in early mammalian development: from gametes to gastrulationSemantic proximity Read

<i>yama</i> , a mutant allele of <i>Mov10l1</i> , disrupts retrotransposon silencing and piRNA biogenesisSemantic proximity Read