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Article

Specialized piRNA pathways act in germline and somatic tissues of the Drosophila ovary.

Cell - 1 May 2009

Malone Colin D, Brennecke Julius, Dus Monica, Stark Alexander, McCombie W Richard, Sachidanandam Ravi, Hannon Gregory J

Abstract excerpt

In Drosophila gonads, Piwi proteins and associated piRNAs collaborate with additional factors to form a small RNA-based immune system that silences mobile elements. Here, we analyzed nine Drosophila piRNA pathway mutants for their impacts on both small RNA populations and the subcellular localization patterns of Piwi proteins. We find that distinct piRNA pathways with differing components function in ovarian germ...

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Identifiers

PMID: 19395010
DOI: 10.1016/j.cell.2009.03.040
PMCID: PMC2882632

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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