Article
piRNAs and their involvement in male germline development in mice.
Development, growth & differentiation - 1 Jan 2012
Pillai Ramesh S, Chuma Shinichiro
Abstract excerpt
Piwi-interacting RNAs (piRNAs) are a class of small non-coding RNAs expressed in the animal gonads. They are implicated in silencing the genome instability threat posed by mobile genetic elements called transposons. Unlike other small RNAs, which use double-stranded precursors, piRNAs seem to arise from long single-stranded precursor transcripts expressed from discrete genomic regions. In mice, the Piwi pathway...
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