Article
Are serum brain-derived neurotrophic factor concentrations related to brain structure and psychopathology in late childhood and early adolescence?
CNS spectrums - 1 Dec 2020
de Araujo Celia Maria, Swardfager Walter, Zugman Andre, Cogo-Moreira Hugo, Belangero Sintia I, Ota Vanessa K, Spindola Leticia M, Hakonarson Hakon, Pellegrino Renata, Gadelha Ary, Salum Giovanni A, Pan Pedro M, Mansur Rodrigo B, Hoexter Marcelo, Picon Felipe, Sato João R, Brietzke Elisa, Grassi-Oliveira Rodrigo, Rohde Luis A P, Miguel Euripedes C, Bressan Rodrigo A, Jackowski Andrea P
Abstract excerpt
OBJECTIVE: Mental disorders can have a major impact on brain development. Peripheral blood concentrations of brain-derived neurotrophic factor (BDNF) are lower in adult psychiatric disorders. Serum BDNF concentrations and BDNF genotype have been associated with cortical maturation in children and adolescents. In 2 large independent samples, this study tests associations between serum BDNF concentrations, brain...
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