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Article

Gray matter volume in adolescent anxiety: an impact of the brain-derived neurotrophic factor Val(66)Met polymorphism?

Journal of the American Academy of Child and Adolescent Psychiatry - 1 Feb 2013

Mueller Sven C, Aouidad Aveline, Gorodetsky Elena, Goldman David, Pine Daniel S, Ernst Monique

Abstract excerpt

OBJECTIVE: Minimal research links anxiety disorders in adolescents to regional gray matter volume (GMV) abnormalities and their modulation by genetic factors. Prior research suggests that a brain-derived neurotrophic factor (BNDF) Val(66)Met polymorphism may modulate such brain morphometry profiles. METHOD: Using voxel-based morphometry and magnetic resonance imaging, associations of BDNF and clinical anxiety...

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Identifiers

PMID: 23357445
DOI: 10.1016/j.jaac.2012.11.016
PMCID: PMC3570270

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Gray matter volume in adolescent anxiety: an impact of the brain-derived neurotrophic factor Val(66)Met polymorphism?PMID 23357445Read ↗

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