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Effects of BDNF polymorphisms on brain function and behavior in health and disease.

Brain research bulletin - 25 Nov 2011

Hong Chen-Jee, Liou Ying-Jay, Tsai Shih-Jen

Abstract excerpt

Brain-derived neurotrophic factor (BDNF), the most abundant neurotrophin in the brain, serves an important role during brain development and in synaptic plasticity. Given its pleiotropic effects in the central nervous system, BDNF has been implicated in cognitive function and personality development as well as the pathogenesis of various psychiatric disorders. Thus, BDNF is considered an attractive candidate gene...

Topics

Brain
Brain-Derived Neurotrophic Factor
Cognition Disorders
Genotype
Humans
Mental Disorders
Neuronal Plasticity
Personality
Polymorphism, Genetic
PubMed

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Identifiers

PMID: 21924328
DOI: 10.1016/j.brainresbull.2011.08.019

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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