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Article

Effect of childhood maltreatment and brain-derived neurotrophic factor on brain morphology.

Social cognitive and affective neuroscience - 1 Nov 2016

van Velzen Laura S, Schmaal Lianne, Jansen Rick, Milaneschi Yuri, Opmeer Esther M, Elzinga Bernet M, van der Wee Nic J A, Veltman Dick J, Penninx Brenda W J H

Abstract excerpt

Childhood maltreatment (CM) has been associated with altered brain morphology, which may partly be due to a direct impact on neural growth, e.g. through the brain-derived neurotrophic factor (BDNF) pathway. Findings on CM, BDNF and brain volume are inconsistent and have never accounted for the entire BDNF pathway. We examined the effects of CM, BDNF (genotype, gene expression and protein level) and their...

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Source

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Identifiers

PMID: 27405617
DOI: 10.1093/scan/nsw086
PMCID: PMC5091678

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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