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Article

Interactive effects of genetic polymorphisms and childhood adversity on brain morphologic changes in depression.

Progress in neuro-psychopharmacology & biological psychiatry - 20 Apr 2019

Kim Yong-Ku, Ham Byung-Joo, Han Kyu-Man

Abstract excerpt

The etiology of depression is characterized by the interplay of genetic and environmental factors and brain structural alteration. Childhood adversity is a major contributing factor in the development of depression. Interactions between childhood adversity and candidate genes for depression could affect brain morphology via the modulation of neurotrophic factors, serotonergic neurotransmission, or the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29535036
DOI: 10.1016/j.pnpbp.2018.03.009

Genes

BDNF
FKBP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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