Article
Interactive effects of BDNF Val66Met genotype and trauma on limbic brain anatomy in childhood.
European child & adolescent psychiatry - 1 May 2016
Marusak Hilary A, Kuruvadi Nisha, Vila Angela M, Shattuck David W, Joshi Shantanu H, Joshi Anand A, Jella Pavan K, Thomason Moriah E
Abstract excerpt
Childhood trauma is a major precipitating factor in psychiatric disease. Emerging data suggest that stress susceptibility is genetically determined, and that risk is mediated by changes in limbic brain circuitry. There is a need to identify markers of disease vulnerability, and it is critical that these markers be investigated in childhood and adolescence, a time when neural networks are particularly malleable...
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