Article
Effects of the BDNF Val66Met Polymorphism on Gray Matter Volume in Typically Developing Children and Adolescents.
Cerebral cortex (New York, N.Y. : 1991) - 1 Apr 2016
Hashimoto Teruo, Fukui Kento, Takeuchi Hikaru, Yokota Susumu, Kikuchi Yoshie, Tomita Hiroaki, Taki Yasuyuki, Kawashima Ryuta
Abstract excerpt
The Val66Met polymorphism of brain-derived neurotrophic factor (BDNF) is associated with psychiatric disorders and regional gray matter volume (rGMV) in adults. However, the relationship between BDNF and rGMV in children has not been clarified. In this 3-year cross-sectional/longitudinal (2 time points) study, we investigated the effects of BDNF genotypes on rGMV in 185 healthy Japanese children aged 5.7-18.4...
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