Article
Effect of a Single Apolipoprotein L1 Gene Nephropathy Variant on the Risk of Advanced Lupus Nephritis in Brazilians.
The Journal of rheumatology - 1 Aug 2020
Vajgel Gisele, Lima Suelen Cristina, Santana Diego Jeronimo S, Oliveira Camila B L, Costa Denise Maria N, Hicks Pamela J, Cavalcante Maria Alina G M, Langefeld Carl D, Valente Lucila Maria, Crovella Sergio, Kirsztajn Gianna Mastroianni, Freedman Barry I, Sandrin-Garcia Paula
Abstract excerpt
OBJECTIVE: Apolipoprotein L1 gene (APOL1) G1 and G2 renal risk alleles (RRA) are associated with endstage renal disease in blacks with lupus nephritis (LN). The present study determined frequencies of APOL1 RRA in nonwhite Brazilian patients with LN and controls to assess association with renal outcomes. METHODS: APOL1 RRA were genotyped in 222 healthy blood donors (controls) and 201 cases with LN from 3...
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