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Article

APOL1-Associated Kidney Disease in Brazil

20 Mar 2019

Abstract excerpt

INTRODUCTION: Coding variants in apolipoprotein L-1 (APOL1) are associated with an increased risk of end-stage kidney disease (ESRD) in African American individuals under a recessive model of inheritance. The effect of the APOL1 risk alleles on kidney disease has been observed in studies in African American and African populations. Despite the 130 million individuals of recent African ancestry in South America,...

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Share to Coagulation, Bradykinin, Polyphosphates, and Angioedema
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PMID: 31317114
DOI: 10.1016/j.ekir.2019.03.006

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