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Article

APOL1 nephropathy - a population genetics success story.

Current opinion in nephrology and hypertension - 1 Jul 2024

Tabachnikov Orly, Skorecki Karl, Kruzel-Davila Etty

Abstract excerpt

PURPOSE OF REVIEW: More than a decade ago, apolipoprotein L1 ( APOL1 ) risk alleles designated G1 and G2, were discovered to be causally associated with markedly increased risk for progressive kidney disease in individuals of recent African ancestry. Gratifying progress has been made during the intervening years, extending to the development and clinical testing of genomically precise small molecule therapy...

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Share to Apolipoprotein L1
Share to Genetic Predisposition to Disease
Share to Genetics, Population

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Oligonucleotides, Antisense

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Source

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Identifiers

PMID: 38415700
DOI: 10.1097/MNH.0000000000000977
PMCID: PMC11139250

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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