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Article

PRODIGY: personalized prioritization of driver genes.

Bioinformatics (Oxford, England) - 1 Mar 2020

Dinstag Gal, Shamir Ron

Abstract excerpt

MOTIVATION: Evolution of cancer is driven by few somatic mutations that disrupt cellular processes, causing abnormal proliferation and tumor development, whereas most somatic mutations have no impact on progression. Distinguishing those mutated genes that drive tumorigenesis in a patient is a primary goal in cancer therapy: Knowledge of these genes and the pathways on which they operate can illuminate disease...

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Identifiers

PMID: 31681944
DOI: 10.1093/bioinformatics/btz815
PMCID: PMC7703777

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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