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Article

PersonaDrive: a method for the identification and prioritization of personalized cancer drivers.

Bioinformatics (Oxford, England) - 27 Jun 2022

Erten Cesim, Houdjedj Aissa, Kazan Hilal, Taleb Bahmed Ahmed Amine

Abstract excerpt

MOTIVATION: A major challenge in cancer genomics is to distinguish the driver mutations that are causally linked to cancer from passenger mutations that do not contribute to cancer development. The majority of existing methods provide a single driver gene list for the entire cohort of patients. However, since mutation profiles of patients from the same cancer type show a high degree of heterogeneity, a more ideal...

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PMID: 35579340
DOI: 10.1093/bioinformatics/btac329

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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