Article
PRODIGY: personalized prioritization of driver genes
2018-10-30
Abstract excerpt
<h4>Background</h4> Evolution of cancer is driven by few somatic mutations that disrupt cellular processes, causing abnormal proliferation and tumor development, while most somatic mutations have no impact on progression. Distinguishing those mutated genes that drive tumorigenesis in a patient is a primary goal in cancer therapy: Knowledge of these genes and the pathways on which they operate can illuminate disea...
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Identifiers and source
- Literature Corpus work
- fd096dd1-09f1-5e11-9457-706da8b008f5
- DOI
- 10.1101/456723