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Article

DriverMP enables improved identification of cancer driver genes.

GigaScience - 28 Dec 2022

Liu Yangyang, Han Jiyun, Kong Tongxin, Xiao Nannan, Mei Qinglin, Liu Juntao

Abstract excerpt

BACKGROUND: Cancer is widely regarded as a complex disease primarily driven by genetic mutations. A critical concern and significant obstacle lies in discerning driver genes amid an extensive array of passenger genes. FINDINGS: We present a new method termed DriverMP for effectively prioritizing altered genes on a cancer-type level by considering mutated gene pairs. It is designed to first apply nonsilent somatic...

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Identifiers

PMID: 38091511
DOI: 10.1093/gigascience/giad106
PMCID: PMC10716827

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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