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Article

Increased plasticity of non-classic Th1 cells toward the Th17 phenotype

12 Sept 2019

Abstract excerpt

Objectives: To analyze occurrence and plasticity of two recently described distinct subtypes of Th1 cells named classic (CD161−/CCR6−) and non-classic (CD161+/CCR6+) Th1 cells in early rheumatoid arthritis (RA) patients and healthy controls (HCs). Methods: Frequencies of in vivo-generated Th1 cell populations were assessed after cytokine secretion assay for IFNγ/IL-17 and surface staining for CD161/CCR6. Viable...

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Identifiers

PMID: 31512538
DOI: 10.1080/14397595.2019.1667473

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