Article
Defining the human T helper 17 cell phenotype.
Trends in immunology - 1 Oct 2012
Annunziato Francesco, Cosmi Lorenzo, Liotta Francesco, Maggi Enrico, Romagnani Sergio
Abstract excerpt
T helper (Th) 17 cells represent a third effector arm of CD4 T cells and complement the function of the Th1 and Th2 cell lineages. Here, we provide an overview of the transcription factors, cytokines, chemokines, and cytokine and chemokine receptors that characterize the Th17 cell phenotype. Data relevant for human Th17 cells are emphasized, with a focus on the function of two markers that have recently been...
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